Copy number variation identification and analysis of the chicken genome using a 60K SNP BeadChip
نویسندگان
چکیده
منابع مشابه
copy number variation detection in sheep genome by using ovine beadchip 50k
introduction recently, genomic research in livestock is focused on genomic variation and its effect on phenotypic performance in economic traits. copy number variation (cnv) is one of these variations in genome including insertion, deletion and duplication of 1 kb to 1 mb segment with more than 90% similarity. cnvs can change gene structure and dosage, can regulate gene expression and function ...
متن کاملGenome-wide Mapping of Copy Number Variations Using SNP Arrays.
The availability of high-density single nucleotide polymorphism (SNP) microarrays in recent years has proven to be a great step forward in the context of global analysis of genomic abnormalities in disease. SNP arrays offer great robustness, high resolution and the possibility to detect a variety of different genomic copy number variations such as submicroscopic deletions, amplifications, loss ...
متن کاملGenome-Wide Mapping of Copy Number Variations and Loss of Heterozygosity Using the Infinium® Human1M BeadChip
IntroductIon Genetic variations within the human genome can take many forms, including single-nucleotide polymorphisms (SNPs), copy number variations (CNVs), and copy-neutral loss of heterozygosity (LOH). SNPs involve the change in a single nucleotide, while CNVs and LOH encompass larger segments of DNA. In this application note, we focus on methods for accurately mapping these structural varia...
متن کاملIdentification of Genome-Wide Copy Number Variations among Diverse Pig Breeds Using SNP Genotyping Arrays
Copy number variations (CNVs) are important forms of genetic variation complementary to SNPs, and can be considered as promising markers for some phenotypic and economically important traits or diseases susceptibility in domestic animals. In the present study, we performed a genome-wide CNV identification in 14 individuals selected from diverse populations, including six types of Chinese indige...
متن کاملCOKGEN: A Software for the Identification of Rare Copy Number Variation from SNP Microarrays
Until fairly recently, it was believed that essentially all human cells harbor two copies of each locus in the autosomal genome. However, studies have now shown that there are segments of the genome that are polymorphic with regard to genomic copy number. These copy number variations (CNVs) have a role in various diseases such as Alzheimer disease, Crohn's disease, autism and schizophrenia. In ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Poultry Science
سال: 2016
ISSN: 0032-5791
DOI: 10.3382/ps/pew136